Bridging Neuroscience and Leadership to Build Human-First, High-Performing Teams
I help leaders translate neuroscience into everyday leadership - aligning the brain and the business to create performance that flows.
Meet Natalie
Natalie Alesi is a global business leader, speaker, and founder of The Interconnected Leader Blueprint - a science-based framework helping leaders create measurable business results through team synchrony, trust, and heart-brain alignment.
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With over two decades leading global Customer Success, SaaS transformation, and strategy at enterprise scale, Natalie has seen what separates teams that perform from those that plateau.
Her work integrates insights from neuroscience, psychology, and human connection to rewire how organizations lead, collaborate, and execute.
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From Global Leadership to Leadership Science
Natalie has spent 20+ years in senior leadership roles across technology and business operations - guiding teams through large-scale digital transformation, customer success optimization, and growth strategy.
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She combines that experience with research from leading institutions such as MIT, Wharton School of Business and the HeartMath Institute, translating complex neuroscience into actionable leadership practices.
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Her research interests include neural synchrony in teams, decision-making under stress, and how self awareness and psychological safety drives measurable performance outcomes - insights backed by data from studies like Google’s Project Aristotle.
Highlights:
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20+ years in SaaS and global customer success leadership
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Focused on team synchrony, trust, and human-centric performance
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Speaker and creator of The Interconnected Leader Blueprint
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Featured in conferences and podcasts exploring the future of leadership
Rewiring Leadership for the Future of Work
Today’s organizations face constant change, dispersed teams, and increasing pressure to deliver results faster.
The challenge isn’t just strategy - it’s human connection.
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Natalie’s philosophy is simple: when leaders align heart and brain, trust follows, and execution accelerates.
Neuroscience confirms that synchrony - the measurable alignment of brainwaves, emotions, and behaviors - predicts trust, creativity, and high performance.
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Her work helps leaders and teams create that alignment intentionally, turning collaboration into a competitive advantage.
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“The future of leadership is both scientific and human - because performance starts in the brain and thrives in human heart connection.” ~ Natalie Alesi
Sharing the Science of Human-First Leadership
Natalie regularly speaks at conferences, podcasts, and executive leadership forums about how neuroscience is redefining performance and engagement in modern organizations.
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Her key topics include:
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The Neuroscience of Team Synchrony
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Psychological Safety and High-Performance Cultures
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Heart-Brain Alignment and Decision-Making
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Leading Remote Teams with Connection and Trust
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Each presentation integrates the latest research with practical, evidence-based strategies leaders can apply immediately.
Beyond the Boardroom
Originally from New Jersey, Natalie brings her trademark energy and authenticity to every room she’s in - whether leading teams, mentoring emerging leaders, or exploring the intersection of neuroscience and leadership.
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When she’s not speaking or building global programs, she’s a proud mom of a teenager, curious learner of neuroscience and heart brain techniques, and lifelong advocate for bringing more humanity and heart into business (and she makes a mean sangria).